{"id":3084,"date":"2013-11-20T15:26:00","date_gmt":"2013-11-20T13:26:00","guid":{"rendered":"http:\/\/www.ced.org.tr\/?p=3084"},"modified":"2013-11-20T15:26:00","modified_gmt":"2013-11-20T13:26:00","slug":"alzheimer-hastaligina-gozden-erken-teshis-umudu","status":"publish","type":"post","link":"http:\/\/www.ced.org.tr\/?p=3084","title":{"rendered":"Alzheimer hastal\u0131\u011f\u0131na g\u00f6zden erken te\u015fhis umudu"},"content":{"rendered":"

14 KASIM 2013 – TS\u0130 16:22<\/span><\/p>\n

Bilim insanlar\u0131, g\u00f6z retinas\u0131ndaki baz\u0131 \u00f6zel h\u00fccrelerde g\u00f6zlenen de\u011fi\u015fikliklerin Alzheimer hastal\u0131\u011f\u0131n\u0131n te\u015fhis ve g\u00f6zetimine yard\u0131mc\u0131 olabilece\u011fini belirtiyor.<\/span><\/p>\n

Bir ara\u015ft\u0131rma ekibi, genetik m\u00fchendislik yoluyla Alzheimer hastas\u0131 yap\u0131lan farelerin retinas\u0131n\u0131 olu\u015fturan h\u00fccre tabakas\u0131nda incelme oldu\u011funu farketti.<\/p>\n

<\/span><\/span><\/p>\n

Ekip, beynin uzant\u0131s\u0131 olan retinada g\u00f6zlenen sinir h\u00fccresi kayb\u0131n\u0131n Alzheimer hastalar\u0131nda g\u00f6r\u00fclen beyin h\u00fccresi kayb\u0131ndan kaynakl\u0131 oldu\u011funa inan\u0131yor.<\/span><\/p>\n

Bulgular ABD N\u00f6robilim Derne\u011fi konferans\u0131nda a\u00e7\u0131kland\u0131.<\/span><\/p>\n

http:\/\/www.bbc.co.uk\/turkce\/haberler\/2013\/11\/131114_alzheimer_retina.shtml<\/a><\/span><\/p>\n

Ara\u015ft\u0131rmac\u0131lar, bu \u00e7al\u0131\u015fma sayesinde gelecekte, rutin g\u00f6z kontrol\u00fc s\u0131ras\u0131nda optisyenlerin Alzheimer te\u015fhisinde bulunmas\u0131n\u0131n m\u00fcmk\u00fcn olabilece\u011fini belirtiyor.<\/span><\/p>\n

Ayn\u0131 retina h\u00fccrelerinde g\u00f6zlenen de\u011fi\u015fiklikler ayr\u0131ca k\u00f6rl\u00fc\u011fe neden olan glukomun da te\u015fhisine yard\u0131mc\u0131 olabilece\u011fi ifade ediliyor.<\/span><\/p>\n

Ucuz ve erken te\u015fhis<\/span><\/strong><\/span><\/p>\n

ABD’deki Georgetown \u00dcniversitesi T\u0131p Merkezi’nden Dr Scott Turner ve ekibi, retinan\u0131n daha \u00f6nce incelenmemi\u015f bir b\u00f6l\u00fcm\u00fcn\u00fc ara\u015ft\u0131rd\u0131.<\/span><\/p>\n

Alzheimer hastal\u0131\u011f\u0131<\/span><\/strong><\/span><\/p>\n

Semptomlar\u0131: Haf\u0131za kayb\u0131, de\u011fi\u015fken ruh hali, ileti\u015fimde ve mant\u0131\u011f\u0131 kullanmada sorunlar<\/span><\/p>\n

Nedeni konusunda hi\u00e7bir fakt\u00f6r belirlenemedi; ancak ya\u015f, gen, \u00e7evre, ya\u015fam tarz\u0131 ve genel sa\u011fl\u0131k gibi fakt\u00f6rlerin etkisi oldu\u011fu d\u00fc\u015f\u00fcn\u00fcl\u00fcyor.<\/span><\/p>\n

Bu konudaki ana teoriye g\u00f6re, beta-amiloid ad\u0131 verilen protein k\u00fcmeleri beyin h\u00fccrelerine zarar vererek \u00f6l\u00fcm\u00fcne neden oluyor.<\/span><\/p>\n

Sadece Alzheimer hastal\u0131\u011f\u0131 olan farelerde bu b\u00f6lgenin kal\u0131nl\u0131\u011f\u0131nda azalma tespit edildi. Bu farelerin retinal ganglion h\u00fccre tabakas\u0131n\u0131n yar\u0131 yar\u0131ya, i\u00e7 \u00e7ekirdek tabakas\u0131n\u0131n ise \u00fc\u00e7te bir oran\u0131nda inceldi\u011fi g\u00f6r\u00fcld\u00fc.<\/span><\/p>\n

Dr Turner, “Bu bulgu, insanlarda bu hastal\u0131\u011f\u0131n geli\u015fimini anlama konusunda yeni bir yol a\u00e7\u0131ld\u0131\u011f\u0131na ve insanlar\u0131n g\u00f6zlerine bakma gibi basit bir y\u00f6ntemle Alzheimer te\u015fhisi veya tahmininde bulunulabilece\u011fine i\u015faret ediyor.” dedi.<\/span><\/p>\n

Ancak bu teorinin hen\u00fcz sek\u00fclasyon a\u015famas\u0131nda oldu\u011funu ve kesinle\u015ftirmek i\u00e7in daha fazla ara\u015ft\u0131rma gerekti\u011fini belirten Scott \u015f\u00f6yle devam etti:<\/span><\/p>\n

“Bu y\u00f6ntemle Alzheimer te\u015fhisinin m\u00fcmk\u00fcn olup olmad\u0131\u011f\u0131n\u0131 g\u00f6rmek i\u00e7in insanlar \u00fczerinde denemek gerekir. Alzheimer i\u00e7in bug\u00fcn kullan\u0131lan biyoi\u015faretler ya \u00e7ok pahal\u0131 ya da invazif. Tomografi yoluyla retinada yap\u0131lacak bir kal\u0131nl\u0131k \u00f6l\u00e7\u00fcm\u00fc ise bunlar\u0131n tam tersi olacakt\u0131r.”<\/span><\/p>\n

\u0130ngiltere Alzheimer Ara\u015ft\u0131rma Derne\u011fi’nden Laura Phipps, retinal h\u00fccre kayb\u0131 ile Alzheimer hastal\u0131\u011f\u0131 aras\u0131ndaki ba\u011flant\u0131ya dair verilerin giderek artt\u0131\u011f\u0131n\u0131 ve ara\u015ft\u0131rmalar\u0131n bu alanda yo\u011funla\u015fmas\u0131n\u0131n olumlu bir ad\u0131m oldu\u011funu ifade etti.<\/span><\/p>\n

Sinirlerde dejenerasyona yol a\u00e7an Alzheimer’\u0131n en yayg\u0131n bi\u00e7imi t\u0131bbi ad\u0131yla demans, halk aras\u0131nda ise bunama olarak bilinen hastal\u0131k. Tedavisi olmayan bu hastal\u0131\u011fa neyin sebep oldu\u011fu da bilinmiyor. Genelde uzun y\u0131llar \u00f6ncesinde ba\u015flam\u0131\u015f olan hastal\u0131k semptomlar\u0131n belirgin hale geldi\u011fi a\u015famaya kadar te\u015fhis edilemiyor.<\/span><\/p>\n

Haf\u0131za kayb\u0131n\u0131 engellemek i\u00e7in hastal\u0131\u011f\u0131 erken te\u015fhis b\u00fcy\u00fck \u00f6nem ta\u015f\u0131yor<\/span><\/p>\n

<\/p>\n

<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

14 KASIM 2013 – TS\u0130 16:22 Bilim insanlar\u0131, g\u00f6z retinas\u0131ndaki baz\u0131 \u00f6zel h\u00fccrelerde g\u00f6zlenen de\u011fi\u015fikliklerin Alzheimer hastal\u0131\u011f\u0131n\u0131n te\u015fhis ve g\u00f6zetimine...<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[62],"tags":[],"class_list":["post-3084","post","type-post","status-publish","format-standard","hentry","category-sagliktan-haberler"],"aioseo_notices":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack-related-posts":[],"_links":{"self":[{"href":"http:\/\/www.ced.org.tr\/index.php?rest_route=\/wp\/v2\/posts\/3084","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.ced.org.tr\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.ced.org.tr\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.ced.org.tr\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.ced.org.tr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3084"}],"version-history":[{"count":0,"href":"http:\/\/www.ced.org.tr\/index.php?rest_route=\/wp\/v2\/posts\/3084\/revisions"}],"wp:attachment":[{"href":"http:\/\/www.ced.org.tr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3084"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.ced.org.tr\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3084"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.ced.org.tr\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3084"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}