{"id":3613,"date":"2009-08-18T12:15:24","date_gmt":"2009-08-18T09:15:24","guid":{"rendered":"http:\/\/www.ced.org.tr\/?p=3613"},"modified":"2009-08-18T12:15:24","modified_gmt":"2009-08-18T09:15:24","slug":"sigara-birakma-ilaclari-icin-fdadan-uyari","status":"publish","type":"post","link":"http:\/\/www.ced.org.tr\/?p=3613","title":{"rendered":"S\u0130GARA BIRAKMA \u0130LA\u00c7LARI \u0130\u00c7\u0130N FDA\u2019DAN UYARI"},"content":{"rendered":"

Champix ve Zyban Kullananlar \u0130ntihar D\u00fc\u015f\u00fcnceleri ve Depresyon Belirtileri Y\u00f6n\u00fcnden \u0130zlenmelidir.<\/span><\/p>\n

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WebMD Health News<\/span><\/p>\n

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1 Temmuz 2009<\/span><\/p>\n

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FDA sigaray\u0131 b\u0131rakmak i\u00e7in kullan\u0131lan Champix ve Zyban adl\u0131 ila\u00e7lar\u0131 kullanan ki\u015filerde g\u00f6r\u00fclen, intihar da dahil olmak \u00fczere garip davran\u0131\u015flar konusunda uyar\u0131 yap\u0131yor.<\/span><\/p>\n

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Her iki ila\u00e7 da art\u0131k ambalajlar\u0131nda bu ila\u00e7lar\u0131 kullanan ki\u015filerin intihar d\u00fc\u015f\u00fcnceleri, depresyon, d\u00fc\u015fmanl\u0131k duygular\u0131 ve di\u011fer davran\u0131\u015f de\u011fi\u015fikliklleri y\u00f6n\u00fcnden yak\u0131ndan izlenmesi konusunda uyar\u0131 i\u00e7eren bir \u201ckara kutu\u201d bulunduracak.<\/span><\/p>\n

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<\/span><\/span>FDA t\u0131bbi politika m\u00fcd\u00fcr\u00fc Dr\u00a0 <\/span>Robert J. Temple . \u201cBiz insanlar\u0131n bu ila\u00e7lar\u0131 kullan\u0131rken dikkatli olmalar\u0131n\u0131 istiyoruz\u201ddiyor.<\/span><\/p>\n

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Bu ila\u00e7lar\u0131n ger\u00e7ekten bu davran\u0131\u015f de\u011fi\u015fikli\u011fine\u00a0 <\/span>neden olup olmad\u0131\u011f\u0131 kesin de\u011fildir. Sigara i\u00e7enler nikotin ba\u011f\u0131ml\u0131s\u0131d\u0131r ve b\u0131rakt\u0131klar\u0131 zaman g\u00f6r\u00fclen yoksunluk semptomlar\u0131 aras\u0131nda intihar da dahil olmak \u00fczere bir \u00e7ok garip\u00a0 <\/span>davran\u0131\u015flar bulunabilir.<\/span><\/p>\n

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Fakat FDA\u2019n\u0131n ila\u00e7 de\u011ferlendirme birimlerinden birinin m\u00fcd\u00fcr\u00fc olan Dr. Curt Rosebraugh, Champix kullananlardan gelen\u00a0 <\/span>intihar raporlar\u0131ndaki ki\u015filerin baz\u0131lar\u0131n\u0131n hala sigara i\u00e7meye devam ettiklerini s\u00f6yl\u00fcyor.<\/span><\/p>\n

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FDA Champix kullanan insanlarda intihar ve garip davran\u0131\u015flar konusundaki raporlar\u0131 izlemektedir.FFA Champix\u2019in pilotlarda kullan\u0131lmas\u0131n\u0131 yasaklam\u0131\u015ft\u0131r.<\/span><\/p>\n

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Bu tip davran\u0131\u015flar ile Zyban aras\u0131ndaki ba\u011f nisbeten yenidir.Zyban\u2019\u0131n aktif maddesi olan bupropion bir antidepresand\u0131r. Antidepresanlar\u0131n ambalajlar\u0131nda \u201cintihar d\u00fc\u015f\u00fcnceleri\u201d uyar\u0131s\u0131 bulunmaktad\u0131r.<\/span><\/p>\n

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FDA y\u0131 en \u00e7ok rahats\u0131z eden raporlar intihar raporlar\u0131d\u0131r.<\/span><\/p>\n

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\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>Champix kullananlardan 98 ki\u015fi intihar ederek \u00f6lm\u00fc\u015f<\/span><\/p>\n

\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>Zyban kullananlardan 14 ki\u015fi intihar ederek \u00f6lm\u00fc\u015f<\/span><\/p>\n

\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>Champix kullanan 188 ki\u015fi intihara te\u015febb\u00fcs etmi\u015f<\/span><\/p>\n

\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>Zyban kullanan 17 ki\u015fi intihara te\u015febb\u00fcs etmi\u015f<\/span><\/p>\n

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Zyban kullananlar ile ilgili raporlar\u0131n say\u0131s\u0131n\u0131n az olmas\u0131 bu ilac\u0131n Champix\u2019den daha g\u00fcvenli oldu\u011fu anlam\u0131na gelmiyor.<\/span><\/p>\n

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FDA Champix\u2019in \u00fcreticisi Pfizer ve Zyban\u2019\u0131n \u00fcreticisi olan GlaxoSmithKline\u2019 dan bu ila\u00e7lar\u0131n ger\u00e7ekten intihara y\u00f6nelik davran\u0131\u015f bozukluklar\u0131na yol a\u00e7\u0131p a\u00e7mad\u0131klar\u0131n\u0131 de\u011ferlendirmek i\u00e7in klinik \u00e7al\u0131\u015fmalar d\u00fczenlemesini istemektedir. \u0130lac\u0131 ruhsatland\u0131r\u0131lmas\u0131ndan\u00a0 <\/span>\u00f6nce yap\u0131lan klinik \u00e7al\u0131\u015fmalar\u0131n aksine, yeni \u00e7al\u0131\u015fmalarda psikiyatrik sorunlar\u0131 da olan sigara i\u00e7en ki\u015filer yer alacakt\u0131r.<\/span><\/p>\n

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\u0130ntihar ve intihar d\u00fc\u015f\u00fcncesi, antidepresanlar, antibiyotikler, akne ila\u00e7lar\u0131, epilepsi ia\u00e7lar\u0131 da dahil olmak \u00fczere \u00e7e\u015fitli ila\u00e7lar ile ba\u011flant\u0131l\u0131 olarak ortaya \u00e7\u0131kmaktad\u0131r.<\/span><\/p>\n

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FDA Warning on Stop-Smoking Drugs; Users of Champix and Zyban Should Be Watched for Signs of Suicidal Thought and Depression
WebMD Health News Reviewed by <\/span>Louise Chang, MD<\/span><\/a> July 1, 2009 <\/span><\/span><\/span><\/p>\n

http:\/\/www.webmd.com\/smoking-cessation\/news\/20090701\/warning-on-stop-smoking-drugs-chantix-zyban<\/span><\/a><\/span> <\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Champix ve Zyban Kullananlar \u0130ntihar D\u00fc\u015f\u00fcnceleri ve Depresyon Belirtileri Y\u00f6n\u00fcnden \u0130zlenmelidir. \u00a0 WebMD Health News \u00a0 1 Temmuz 2009 \u00a0...<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_monsterinsights_skip_tracking":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[1],"tags":[],"class_list":["post-3613","post","type-post","status-publish","format-standard","hentry","category-ced"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\t\n\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t